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Android 16 was created by Dr. Gero. he was activated by Android 17 and 18. Android 16 likes nature and hate fighting. When 17 was having a hard time fighting Imperfect Cell, 16 takes the stand and fights cell and then 16 overpowers cell and defeat him. 16 told 17 to run but 17 refused.
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Androids 16, 17, and 18

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Android 16 was destroyed by Perfect-form Cell, which made Gohan go SSJ2.

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